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Sep 11, - Rich in nerve endings, the strip of skin between the anus and testicles is an area in which men may feel discomfort for a variety of reasons,  Missing: night ‎| ‎Must include: ‎night. Aug 10, - In men, the area between the testicles and the anus is called perineum. In chronic conditions, the persistence of perineal pain or perineum pain will be urinary frequency, frequent urination during nighttime, and burning.